• Theragnostics combines diagnostic imaging with radionuclide therapy, allowing healthcare professionals to both diagnose and treat cancer in a highly targeted manner. This approach uses radiopharmaceuticals that target application specific cancer cells to provide personalized treatment while minimizing damage to healthy tissues.

    The RATIONALE network (COST Action Ca22118) is a European initiative that fosters collaboration between experts involved in radionuclide theragnostics. The project focuses on optimizing theragnostic procedures, standardizing dosimetry, and facilitating the clinical translation of theragnostic research into personalized cancer treatments. Further, RATIONALE sets a strong focus on enhancing theranostic education in Europe and beyond.

    Theragnostics is primarily used for treating of thyroid cancer, neuroendocrine tumors and prostate cancer. Ongoing research aims to expand its use to other cancer types, including some that are currently under investigation in clinical trials.

    Dosimetry means the assessment of the amount of radiation absorbed by the tumor and healthy tissues, allowing for personalized treatment plans that maximize effectiveness and minimize side effects. Standardizing dosimetry and enhancing its accessibility across theragnostic centers is a key goal of the RATIONALE project.

    Healthcare professionals, researchers, industry experts and other persons involved in theragnostics can participate in the RATIONALE project by joining working groups, attending training events, or applying for grants. The project aims to advance theragnostics research and clinical applications through collaboration across Europe and beyond.

  • Education

    RATIONALE provides educational programs and materials such as workshops, webinars, and training schools. These programs aim to enhance knowledge in theragnostics, particularly in regions with limited access to specialized education in this field.

    RATIONALE aims on providing guidance and help in integrating theragnostic education into local curricula and researcher training programs across Europe, ensuring that healthcare professionals have access to the latest techniques and knowledge .

    RATIONALE offers a variety of educational resources, including case studies, webinars, and training modules, all of which are available online to support ongoing education for healthcare professionals.

  • Events

    RATIONALE hosts a variety of events, including workshops, and training schools focused on theragnostics. These events are designed to facilitate knowledge exchange and collaboration among experts.

    Registration for RATIONALE events can be completed online via the event details page. Each event includes an overview of the agenda, speakers, and training topics.

    Yes, RATIONALE seeks to provide access to recordings, presentations, and other materials from past workshops and conferences. These resources are available on the website for those who were unable to attend.

  • Case studies

    A theragnostic case study documents the diagnostic work up and treatment of a specific cancer patient using radionuclide therapy. These studies provide valuable insights into the practical application of theragnostics in clinical settings.

    RATIONALE provides a collection of case studies on the website. These case studies highlight successful treatment approaches and illustrate the benefits of personalized cancer therapies.

    Yes, RATIONALE encourages healthcare professionals to contribute case studies that showcase their experiences with theragnostic treatments. These contributions help expand the body of knowledge and support ongoing research efforts.